Extubation and the myth of "minimal ventilator settings".

the foundation of improvement. Ann Intern Med 1998;128:1004–1009. 4. Collins FS. Re-engineering translational science: the time is right. Sci Transl Med 2011;3:1–6. 5. National Institutes of Health. The CRADA initiative [Internet; accessed 2011 Sept 15]. Available from: http://www.ott.nih.gov/cradas/model_ agree.aspx 6. National Institutes of Health. The TRND initiative [Internet; accessed 2011 Sept 15]. Available from: http://trend.nih.gov/ 7. Innovative Medicines Initiative [Internet; accessed 2011 Sept 15]. Available from: http://www.imi-europe.org/ 8. Foundation for the NIH [Internet; accessed 2011 Sept 15]. Available from: http://www.fnih.org/support/foundation/research-partnership 9. Glass B. The ethical basis of science. Science 1965;150:1254–1261. 10. Hyatt HH. Protecting the medical commons: who is responsible? N Engl J Med 1975;293:235–241. 11. Petak SM, Coble YD, Duick DS, Gonzales-Campoy JM, Hodgson SF, Lefferts JD, Williams FA, Zeiger MZ. American Association of Clinical Endocrinologists and American College of Endocrinology: position statement on physician/industry relationships. Endocr Pract 2009;15:289. 12. Levinsky NG. Non-financial conflicts of interest in research. N Engl J Med 2002;347:759–761. 13. Beecher HK. Ethics and clinical research. N Engl J Med 1966;274:1354– 1360. 14. MacIntyre A. After virtue: a study in moral theory, 3rd ed. Notre Dame, IN: University of Notre Dame Press; 2007.